Chicago @ Atlanta - Michael Turner and the Falcons continue their recent hot streak with a tough win against the Bears.
The Pick: Atlanta
Baltimore @ Indianapolis - Look for the two smartest players in the NFL (Peyton Manning and Ray Lewis) to duel it out in Indy. Baltimore's stingy swarming defense takes care of the struggling Colt offense.
The Pick: Baltimore
Detroit @ Minnesota - Minnesota weathered Hurricane Reggie in New Orleans and should have no problem with the pitiful Lions.
The Pick: Minnesota
Oakland @ New Orleans - The first game after Lane Kiffin was fired and first since Tom Cable was hired turns for the worse as Saints' Brees and Bush terrorize Raider D.
The Pick: New Orleans
Cincinnati @ NY Jets - Ryan Fitzpatrick gets the start for Cincinnati's struggling offense and should have an okay game but not as good as #4 on the other side.
The Pick: NY Jets
Carolina @ Tampa Bay - NFC South battle in Tampa becomes a heavyweight slugfest with two talented defenses. Panthers' defensive line takes care of business.
The Pick: Carolina
St. Louis @ Washington - No comment needed.
The Pick: Washington
Miami @ Houston - If the "Wildcat" offense keeps succeeding, Ronnie Brown will be tough to stop.
The Pick: Miami
Jacksonville @ Denver - Game of the week between desperate Jaguars and lucky Broncos. Jay Cutler tries to avoid Jacksonville's pass rush while Jacksonville ground game gets back on track.
The Pick: Jacksonville
Dallas @ Arizona - If you love offensive fireworks, this is your game. Tony Romo and Kurt Warner post absurd passing numbers, but Cowboys' defense should be enough to win.
The Pick: Dallas
Philadelphia @ San Francisco - Eagles enter game fired up following McNabb's "embarrassing" comments and take out anger on Niners.
The Pick: Philadelphia
Green Bay @ Seattle - Packers have been rolling offensively while Seahawks have been struggling.
The Pick: Green Bay
New England @ San Diego - Disappointing 2-3 Chargers return home to take on the Matt Cassell-led Patriots. LT snaps out of his funk and Bolts finally get a good win.
The Pick: San Diego
NY Giants @ Cleveland - Monday Nighter pits dominating Giants against underachieving Browns. Plaxico Burress returns for New York, giving them just another weapon to unleash against Cleveland.
The Pick: NY Giants